British Air Force Typhoon FGR4s have operated alongside French warplanes in a joint strike targeting an subterranean weapons facility in Syrian territory employed by the IS group, per a report from the UK Ministry of Defence.
The location, located using reconnaissance, was believed to be housing weapons and explosive materials, the statement said, and was located in mountains just north of the historic site of Palmyra in central Syria.
"The RAF jets utilized laser-guided Paveway IV weapons to strike a series of approach shafts leading to the depot... initial indications suggest the target was engaged successfully," the MoD said.
There was no evidence of any civilian impact in the operation conducted Saturday night and every plane involved returned safely, the ministry further stated.
The Typhoon FGR4s were supported by a Voyager refuelling tanker.
IS - referred to as Daesh - imposed jihadist rule over parts of both Syria and Iraq until 2019.
"This strike underscores the UK's leading role, and determination to stand shoulder to shoulder with allied nations, to eliminate any re-emergence of IS and their violent and radical beliefs in the region," the British Defence Secretary John Healey stated.
UK warplanes have carried out overwatch operations over Syria to "forestall any attempted resurgence" of IS after its routing at the climactic battle in Baghuz in 2019, the authorities noted.
"I want to thank all the members of our armed forces involved in this mission for their skill and their courage," the Defence Secretary added. "They were part of thousands of UK service members on duty over the holidays. This mission, to take out dangerous terrorists who endanger our safety, shows how our armed forces are always on standby, continuously, protecting the UK within its borders and influential overseas."
In December, the American forces conducted what it called a "large-scale strike" against Islamic State objectives in the country, after an ambush claimed the lives of two American soldiers and a civilian interpreter in the Palmyra area.
The UN reports IS still boasts an estimated 5,000 to 7,000 combatants in Iraq and Syria.